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Careers

We Put People First

At Autobahn, our mission, approach and commitments are centered entirely around people…

People affected by CNS disorders, including their families and physicians, who deserve to feel hopeful about their treatment options and future.

People who work tirelessly each day to create life-changing medicines.

People who collaborate with us, not just to improve, but fundamentally transform the lives of patients with CNS disorders.

Group photo of Autobahn team

Our Team

Our team is a group of extraordinarily talented individuals with the passion and commitment required to move mountains. We’re serious about our work but always make sure that we pause to breathe and to recognize that the journey is as important as the destination. Our sunny San Diego location is the perfect environment to help us get outside and take a moment for ourselves.

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Our Values

Culture of Integrity

Thoughtful purpose yields trusted outcomes. We abide by an inherent obligation to do the right thing for the right reasons, every time. Our journey is paved by being open, balanced and respectful in all of our actions, engagements and decisions.

Spirited Collaboration

Ambitious goals require teams to collaborate at the highest level – uniting our diverse knowledge, ideas and talents to accomplish a singular mission. Collaboration drives innovation, efficiency and success. It’s also fun!

Results-Driven

We work with exceptional people who do exceptional things. With a bold vision and a can-do attitude, we challenge the notion of what’s possible, not just to meet the needs of those we touch, but to exceed them.

Join us in our mission

As a start-up company, we are always seeking exceptional people who do exceptional things to take us to exceptional levels. Just because we may not have your ideal position posted at this moment, doesn’t mean we won’t have a position matching your talent in the near future.

Autobahn is headquartered in brand new facilities at Alexandria GradLabs in San Diego. In addition to a competitive compensation package that includes equity incentives, we offer a comprehensive benefits package for our employees and their families, which includes:

  • Robust benefits – broad range of medical, dental and vision plans, plus FSA
  • Wellness – free membership to fitness centers and classes
  • Life – unlimited PTO, holidays, discounted tickets
  • Financial security – 401(k) plan, life and disability insurance
  • Having fun – team building events and great GradLabs amenities, including catered lunches and food trucks

Director, Program Management

Join Autobahn Therapeutics! We are seeking high-performing individuals who are passionate about science and excited to work in a collaborative environment with an experienced team fueled by a rigorous and entrepreneurial culture. Take part in our mission to restore hope for people affected by CNS disorders.

Apply to Position

About

Autobahn Therapeutics is focused on improving life health for people affected by CNS disorders. Autobahn is leveraging a deep understanding of validated human biology coupled with its brain-targeting chemistry platform to develop thyroid hormone receptor beta agonist therapies that harness the regenerative power of the human body. The company’s pipeline is led by ABX-002 for the treatment of multiple sclerosis and adrenomyeloneuropathy (AMN), a rare genetic disorder.

Autobahn Therapeutics has a deep investor base, anchored by ARCH Venture Partners, and is located in San Diego. For more information, visit www.autobahntx.com.

Responsibilities

The Director, Program Management will report directly to the SVP, Development Operations and Program Management and work closely with both the SVP, Development Operations and Program Management and Program Champion to implement and execute the strategy and plans to deliver our long-term objectives for key assets in the portfolio.  The Director, Program Management will have direct responsibility for leading an early stage product development team that is transitioning a compound from research to development, including long-range planning to support NDA approval(s) and launch.

Key Responsibilities

  • In collaboration with the Program Champion, develops and ensures successful execution of the Product Development Team’s (PDT) strategy and cross functional operational plans.
  • Leads the PDT, including overseeing program management activities, team meetings, scenario planning, managing project objectives and integrated program plans, and budget approvals for key activities
  • Responsible for providing formal and informal status updates to internal and external stakeholders, as needed.
  • Establishes and maintains program monthly dashboard and functionally integrated project schedules to enable accurate analyses, identification of critical path activities, and areas of resource constraint.
  • Manages risk mitigation strategies, assesses project risk and supports mitigation planning and tracking.
  • Leads and facilitates cross-functional communication and decision making, ensuring alignment with internal functional groups and the executive leadership team.
  • Develops relationships with all key internal stakeholders across the organization as well as the external stakeholders (consultants) that are active participants on the PDT.
  • Identifies opportunities for business process improvements and recommends solutions.
  • Manages key external vendor activities and associated budget, when required.

Requirements

Education

  • Minimum of a BS/BA degree and 10-15 years of multi-disciplinary program management experience in the pharmaceutical/biotechnology industry.

Experience

  • Experience with both early and late phase pharmaceutical program management, including leading teams through successful IND/CTA and NDA/MAA submissions.
  • Successful track record of managing complex cross-functional programs, including knowledge of drug development process and inter-dependencies of key functions to include research, pharmaceutical development, non-clinical, clinical research, clinical operations, manufacturing, regulatory, medical affairs, marketing and commercial operations
  • Excellent program leader (that can successfully manage a team virtually and in person) and team member with a strong willingness and ability to work in a fast-paced, entrepreneurial environment
  • Applies in-depth knowledge of own function, business / commercial / scientific expertise to solve critical issues successfully and innovatively
  • Evaluates key business / scientific challenges and completes complex, ambiguous initiatives having cross-functional impact
  • Advanced knowledge of project management practices, tools and methodology is a plus.

Attributes

  • Outstanding written, verbal and interpersonal communication skills, with the ability to effectively interact with individuals at all levels across the organization
  • Ability to lead, drive consensus and decision-making

 

In addition to a competitive compensation package with stock options, we also offer a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, life, disability and a 401(k) plan.

For consideration, please submit your resume and cover letter referencing job PM024 to careers@autobahntx.com

Director, Clinical Operations

Join Autobahn Therapeutics! We are seeking high-performing individuals who are passionate about science and excited to work in a collaborative environment with an experienced team fueled by a rigorous and entrepreneurial culture. Take part in our mission to restore hope for people affected by CNS disorders.

Apply to Position

About

Autobahn Therapeutics is focused on improving life health for people affected by CNS disorders. Autobahn is leveraging a deep understanding of validated human biology coupled with its brain-targeting chemistry platform to develop thyroid hormone receptor beta agonist therapies that harness the regenerative power of the human body. The company’s pipeline is led by ABX-002 for the treatment of multiple sclerosis and adrenomyeloneuropathy (AMN), a rare genetic disorder.

Autobahn Therapeutics has a deep investor base, anchored by ARCH Venture Partners, and is located in San Diego. For more information, visit www.autobahntx.com.

Responsibilities

The successful candidate will identify, lead and oversee operational resources related to CNS-driven drug discovery programs, including managing direct reports (CRAs) and vendors. The Director, Clinical Operations will be accountable for the efficient planning, execution, oversight, and delivery of the highest quality clinical trials according to required standards and regulations (SOPs, ICH GCP, regulations, data privacy, etc.).

Key Responsibilities

  • Perform all duties in keeping with the Company’s core values, policies and all applicable regulations
  • Support the SVP, Translational Medicine to build and lead Clinical Operations (e.g. governance, resources, budget, SOPs, vendors, etc.)
  • Alongside HR, direct and oversee recruitment, hiring, onboarding, mentoring, and provide line management of direct reports (i.e. CRAs)
  • Identify, qualify and oversee additional resources required to deliver projects compliantly, effectively and efficiently (i.e. CROs, vendors, consultants/medical writers, Key Opinion Leaders, etc.)
  • Utilize best practice operational, project, change and risk management strategies to plan, oversee and report timely, high quality programs/projects (trials), ensuring regulatory compliance and ongoing audit/inspection readiness
  • Demonstrate initiative and willingness to perform activities necessary to ensure that organizational and project deliverables are achieved
  • Drive development of and/or, provide expertise, to generate operationally feasible organizational, program and trial level documentation and procedures (e.g. SOPs, protocol, Investigators’ Brochure, consent/patient information, monitoring plans, safety review committee charters, etc.)
  • Evaluate the health and success of program/project deliverables (time, budget, scope) to ensure they remain on track, making adjustments where necessary (applying appropriate company resources/systems/tools as needed)
  • For all programs/projects, proactively identify and manage ‘issues that matter’ and address noncompliance, applying judgement to ensure appropriate issue responses, escalations and timely resolution. Perform root cause analyses and take corrective and preventive actions, where necessary
  • Proactively collaborate with stakeholders to communicate information effectively. Prepare and present updates and reports, as required
  • Liaise with regulatory agencies to support filing/application activities, review and approval process (IND, etc.)
  • Maintain awareness of current and evolving industry trends, regulations and best practices to ensure that company continually improve and adapt accordingly
  • Continually evaluate lessons learned and assess the impact on company infrastructure and address potential gaps and identify improvement opportunities
  • Ensure continuity of professional development and learning, proactively exploring opportunities to network and enhance competencies (and for direct reports)
  • Apply commercial, financial and business acumen skills to all endeavours

Requirements

Education

  • Bachelor’s degree (RN or equivalent) is required.
  • Master’s degree or higher degree is welcome.

Experience

  • Significant US and international clinical operations/project management experience in the biopharmaceutical industry, including direct experience in biotech and early clinical development (Phase Ib/IIa clinical trials) is required.
  • Deep knowledge of drug development, ICH/21CFR/EMA clinical trials regulations and clinical operations roles and responsibilities is required.
  • Previous line management and hiring experience
  • Experience selecting, qualifying and overseeing CROs/vendors/consultants
  • Experience and knowledge of FDA/EMA IND/NDA submission and approval process
  • CNS and/or rare disease experience is highly desired
  • Early development clinical monitoring experience is desired
  • 15 years CRO experience in biotechnology, life sciences, pharmaceuticals is ideal
  • Systematic, analytical and critical thinker – able to evaluate complex information and apply data-driven approaches to ensure effective decision making and solutions.
  • Advanced program/project management skills
  • Ability to provide flexible and scalable operational solutions to aid effective planning and implementation of governance/systems/programs/trials
  • Ability to proactively evaluate and communicate the impact of risk and change on organisations, projects and deliverables – proficient in application of best practice project and risk based quality management approaches
  • Advanced verbal and written communication and negotiation skills, with an ability to build effective relationships across international cultures and organizations
  • Advanced presentation skills – able to simplify and distill complex information for stakeholders at all levels to enable efficient and effective decision making
  • Ability to build and sustain a team of direct reports and contractors – develop, coach, train and mentor others

Attributes

  • Transparency, humility, accountability, collaborative, inclusive leadership, high level of EI/adaptability/resilience – awareness of unconscious bias, uses influencing skills to remove barriers, agile, promotes sharing and applying lessons learned, change champion, big picture thinker, flexible, self-motivated
  • Shows willingness to ‘jump-in’ and get the work done when/where it’s needed,
  • Behavioral based interviewing experience, developing competencies for key roles based on industry best practice.
  • Ability to function effectively in an organisation where there is very little infrastructure in place (has worked in biotech before).
  • Critical thinking – Asks the right questions at the right time and understands how RBQM can be applied within Early dev/rare disease studies (scalable approach).
  • Knows what regulatory changes are coming and can keep up to date/assess impact on wider organisation.
  • Strives for excellence (rather than perfection).

In addition to a competitive compensation package with stock options, we also offer a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, life, disability and a 401(k) plan.

For consideration, please submit your resume and cover letter referencing job 011MED to careers@autobahntx.com

Director, Translational Neuroscience

Join Us! We are seeking high-performing individuals who are passionate about science and excited to work in a collaborative environment with an experienced team fueled by a rigorous and entrepreneurial culture. Take part in our mission to restore hope for people affected by CNS disorders.

Apply to Position

About

Autobahn Therapeutics is focused on improving life health for people affected by CNS disorders. Autobahn is leveraging a deep understanding of validated human biology coupled with its brain-targeting chemistry platform to develop thyroid hormone receptor beta agonist therapies that harness the regenerative power of the human body. The company’s pipeline is led by ABX-002 for the treatment of multiple sclerosis and adrenomyeloneuropathy (AMN), a rare genetic disorder.

Autobahn Therapeutics has a deep investor base, anchored by ARCH Venture Partners, and is located in San Diego. For more information, visit www.autobahntx.com.

Responsibilities

Join an experienced team with a track record of success! The successful candidate will design, implement, and interpret internal and external advanced preclinical pharmacology studies to support Autobahn’s preclinical programs. Develop and implement preclinical and clinical biomarker strategies to support clinical development of Autobahn CNS-driven drug discovery programs.As biomarkers can encompass many technical platforms and may have various levels of preclinical and clinical utility, the successful candidate will ably learn about new technologies and manage external consultants specific for those techniques.

Key Responsibilities

  • Take end-to-end responsibility for the selection of biomarker strategies and their integration into Discovery to inform compound selection and dose targets, and their utility to inform clinical decision-making.
  • Design and execute translational research plans that integrates both disease and pathway approaches
  • Develop biomarker strategies to enable preclinical programs to drive formulation of biomarker strategy at an early stage of development.
  • Conduct biomarker assay development. Oversee validation and suitability for clinical use. Work with clinical development experts to manage integration into clinical workstream and decision-making.
  • Provide expert guidance to multi-disciplinary teams and senior management; act as the Biomarker representative on Project teams.
  • Provide regular presentations of rationales, key data, issues, and accomplishments to members of the cross-functional discovery team and to the broader organization.
  • Manage pharmacology research studies at CROs and external academic collaborators.  External pharmacology studies will be strategically integrated to complement internal Discovery efforts, and will provide an opportunity for external visibility of Autobahn progress.

Requirements

Qualifications

Education

  • Ph.D. in Neuroscience with 5+ years industrial experience in CNS drug discovery

Experience

  • Significant experience in advanced models of CNS disorders, strong understanding of PK/PD and biomarker approaches to drug discovery, and biomarker discovery and development, assay development/validation. Knowledge of clinical discovery of biomarkers, and MoA/translational research.
  • Demonstrated ability to think-through and communicate criteria by which biomarkers should influence Discovery and Development.
  • A deep knowledge of biochemical, ADME, physicochemical, and pharmacological principles allowing for the independent design of translational studies and biomarker studies.

Attributes

  • Strong experimental background and experience in hypothesis-driven biological/translational research with demonstrated ability to execute well-designed, creative experiments.
  • Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast-paced and dynamic, team-oriented environment.
  • Excellent collaboration, communication, and interpersonal skills are required to engage and be productive within a high achieving team environment.
  • Ability to integrate complex scientific ideas, generate testable hypotheses, and execute broad understanding of drug discovery and development in pre-clinical development
  • Proven scientific/leadership expertise (working in teams, managing people/projects commensurate with a senior level).
  • Strong problem-solving skills with a high level of creativity and productivity

In addition to a competitive compensation package with stock options, we also offer a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, life, disability and a 401(k) plan.

For consideration, please submit your resume and cover letter referencing job 016MED to careers@autobahntx.com

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